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Hydroxychloroquine skin rash pictures

Just diagnosed with RA a few months ago. Started this medication 200 mg of hydroxychloroquine and after 3.5 weeks I broke out with rash on belly . Stopped taking it a little over a week ago. Rash has spread to let's, arms and chest with hard little bumps on skin as well. Sun makes it worse Hydroxychloroquine is particularly effective for systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE). By reducing inflammation, hydroxychloroquine can decrease pain, swelling and stiffness of joints, and improve or clear some rashes. Which skin conditions are treated with hydroxychloroquine? These include Hydroxychloroquine (Plaquenil®) is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus (SLE), rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action

Background: Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. Objective To determine if adverse cutaneous eruptions due to. View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced rash. Reports are from official medical reports as well as online extractions from user reviews and forum discussions The maculopapular rashes are uncommon, cutaneous eruptions that are characterized by erosions and bleeding of lesions over the body. 5 The medicines which are usually implicated in cases of pustulosis are antibiotics like macrolides, cephalosporins and hydroxychloroquine produce the positive therapeutics action on inflammatory arthritis and.

Rash with hydroxychloroquine?: Just diagnosed with RA a

Article updated March 10, 2020. Autoimmune diseases come in a variety of forms, each affecting different organs and bodily systems and producing a unique array of symptoms.While some of these symptoms may often be invisible, skin manifestations can often be one of the most visible and telltale signs of autoimmune disease. Autoimmune diseases are conditions where the immune system. Small vessel vasculitis is the most common form of vasculitis affecting arterioles and venules. In the skin, small vessel vasculitis presents with palpable purpura. Cutaneous small-vessel vasculitis can be idiopathic / primary, or secondary to infection, drug or disease. It may be neutrophilic, lymphocytic or granulomatous on histopathology Symptoms. Most of the symptoms of porphyria cutanea tarda appear on the skin. Common symptoms include: blisters on skin that's exposed to the sun, including the hands, face, and arms. Granuloma annulare (GA) is skin disorder that most often causes a rash with red bumps (erythematous papules) arranged in a circle or ring pattern (annular). GA is not contagious and is not cancerous. The rash may be localized or generalized. Localized GA is the most common form of GA (75% of the cases) and usually affects the forearms, hands, or feet

Maculopapular rashes could even be an assortment of hasty characterized by grade, ruddy region on the skin that is secured with little intersecting bumps. During this case, a 55-year-old woman patient has developed maculopapular rashes over the body. It is a medical reaction caused because of the hydroxychloroquine, which th Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight

Hydroxychloroquine Skin Suppor

Skin conditions associated with lupus are fairly significant and a major marker of the disease. Of the eleven criteria set by the American College of Rheumatology for a diagnosis of lupus, four are skin-related. These include: Malar rash - butterfly rash that appears on the cheeks; Discoid rash - red patches on the skin that can lead to. Oral hydroxychloroquine pills; Although there is no cure for lichen planus, treatment can usually minimize symptoms and improve the appearance of the rash until it heals. Trusted Links MedlinePlus: Skin Conditions Clinical Information and Differential Diagnosis of Lichen Planus References. Bolognia, Jean L., ed. Dermatology, pp.175-184. New. She stopped the hydroxychloroquine but within 24 h the rash had become exfoliating, and she developed oral ulceration and hypotension. This required a 3‐day hospital admission and treatment with intravenous followed by high‐dose oral (60 mg) and topical steroids, which resulted in gradual improvement Hydroxychloroquine is very commonly used in rheumatology, and patients are advised to stop the drug if a rash develops. However, often the drug reaction is misdiagnosed either as a flare of systemic lupus erythematosus or as another form of cutaneous reaction Showing 1 - 13 of 13 for plaquenil rash pictures. (0.005 seconds) Some questions about lupus? Jul 23, 2005 Yes I do have skin rashes that come and go. From the pictures I have seen on the web they appear to be similar to SCLE annular rash. As I am not an expert I can not verify. I'll show them to the rhumy on the next visit..

Hydroxychloroquine DermNet N

  1. The rash tends to be itchy and can lead to trouble sleeping for many people. Although the skin rashes frequently fade completely, they may be followed by brownish discolorations (hyperpigmentation) of the skin, atrophy, scarring, and/or loss of color (depigmentation) of patches of skin (vitiligo). such as hydroxychloroquine, may be useful.
  2. A skin rash is a possible symptom of COVID-19. The symptom has emerged in research studies of COVID-19 patients and as more is learned about the infection. See pictures of distinct types of COVID.
  3. Re: Plaquenil and skin discoloration. « Reply #11 on: April 21, 2009, 08:10:15 PM ». Hyper-pigmentation is a possible side effect of chloroquine medications, chloroquine binds with melanin, causing patchy or mottled spots on areas of skin exposed to sunlight. The spots can range in colors from blueish to brown in color
  4. Dermatomyositis is an inflammatory disease of the muscles, characterized by a skin rash and muscle inflammation followed by muscle weakness. It is also considered an autoimmune disease, because the disorder results from the body's immune system attacking it's own tissues. It is related to other inflammatory myopathies, such as polymyositis.
  5. Exercise-induced vasculitis is a harmless form of cutaneous small vessel vasculitis. It is also called golfer's vasculitis. It is a neutrophilic inflammatory disorder involving the small or medium-sized blood vessels of the skin and subcutaneous tissue. When only the small capillary vessels are involved, it is also called exercise-induced.
  6. Contact dermatitis - the main symptom is a rash that happens where your skin has touched something that you are allergic to such as a new deodorant, new perfume, etc. In addition to the rash you may also have blisters, itching, and redness. Long-term allergic reaction rash - with this type the symptoms are usually more severe
  7. Rosacea: A common skin condition, rosacea may appear as red skin on the face with telangiectases or even pus-filled bumps that resemble acne. Skin can be sensitive and easily irritated. It is often difficult to distinguish whether a face rash is the result of sunburn, rosacea or SLE

Photosensitivity, sometimes referred to as a sun allergy, is an immune system reaction that is triggered by sunlight. Sunlight can trigger immune system reactions. People develop itchy eruptions or areas of redness and inflammation on patches of sun-exposed skin. The diagnosis is usually based on a doctor's evaluation intolerable grade 2 rash . 3 [Photo] > 30% of BSA : Consider interruption or discontinuation . Treat with oral antihistamines or oral corticosteroids until rash is grade ≤ 1; consider dose interruption : 4 . patchy, raised, macular skin lesions, sometimes with localize

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular. They'd previously tried Plaquenil (worsened rash), cyclosporine (couldn't tolerate) and Cellcept (developed severe flu-like symptoms). What Ellen described as a rash was actually a collection of different skin problems, including contact dermatitis of unknown etiology, eczema (atopic dermatitis), hives and dermatographism However, most skin lupus patients do require some type of oral therapy in addition to the topical therapy. The safest form of oral therapy to treat lupus skin disease would be one, or a combination, of the anti-malarial drugs, such as hydroxychloroquine, which is commonly referred to by its trade name: Plaquenil

Lupus rash and skin changes often accompany other symptoms of lupus, which can include fatigue, pain and swelling in the joints, and swollen glands. The outward manifestations of lupus on the. Summary: Rashes is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for < 1 month. The phase IV clinical study analyzes which people take Plaquenil and have Rashes. It is created by eHealthMe based on reports of 64,140 people who have side effects when taking Plaquenil from the FDA.

Adverse cutaneous reactions to hydroxychloroquine are more

Hydroxychloroquine is a medicine used to prevent and treat malaria (a disease caused by parasites that enter the body via a mosquito bite). It's also given to help certain autoimmune diseases. Quineprox 500 Mg. After a good feedback is acquired in rheumatoid joint inflammation with the preliminary recommended dose (typically in 4 to 12 weeks), the dosage is decreased by 50 % (upkeep dosage). Dermatologic Reactions: Bleaching of hair, alopecia, pruritus, skin as well as mucosal pigmentation, photosentivity, and skin eruptions. a serious drug reaction that can affect many parts of your body--skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye Dry, scaly skin patches. Burning sensation on your skin. Lesions that looks similar to Eczema. The skin of the area that is affected by photodermatitis may become scarred if this skin condition persists over a long period of time. If it is a severe case of photodermatitis you may also have flu-like symptoms like nausea, vomiting, fever, and.

Hydroxychloroquine-induced inverse psoriasis | BMJ Case

This is mainly affects lower limbs and causes pain and skin ulceration without any inflammation. Dermatomyositis. This may affects at any age. Distinct skin rashes, muscle weakness and inflammation are the main features of this condition. This condition is also attributed inflammation of the blood vessels and leads to Livedo reticularis. Lymphom Hydrocortisone cream is typically applied to the affected area of skin from two to three times per day, but a prescription cream may be used less frequently. 1  Apply the cream thinly, rubbing it in until fully absorbed. Treatment can last anywhere from a few days to a few weeks until the rash and itchiness have resolved Buy Plaquenil (Hydroxychloroquine) Online | Mail Order Pharmacy . It takes a team to provide effective, compassionate care and our team is dedicated to serving those needs. Hydroxychloroquine and sulfasalazine. Hydroxychloroquine (Plaquenil) is an older DMARD sometimes still used for mild RA. Plaquenil is used with other medications to. Plaquenil has been described as a Mother's Milk for rheumatiod arthritis symptoms, but they found that it's also the only known med to control the skin rash associated with discoid lupus! Read More If a doctor suspects this condition, a skin biopsy needs to be done to confirm the diagnosis because other conditions can look like discoid lupus. A rash is an area of swollen, irritated skin that manifests in different patterns and varying shades of red, purple or brown. Some rashes are caused by allergic reactions to the environment, food or medications, while others appear because of a skin disorder or underlying disease or infection

Adverse Cutaneous Reactions to Hydroxychloroquine Are More

Plaquenil is a prescription medication approved by the Food and Drug Administration (FDA) in 1955. Plaquenil is sometimes prescribed to treat inflammation in people with psoriatic arthritis. Plaquenil is also known by its drug name, Hydroxychloroquine. Plaquenil should be used with caution in people with skin symptoms of psoriasis since it can. DISCUSSION. Leflunomide, an inhibitor of pyrimidine synthesis, has recently been introduced in the treatment of patients with rheumatoid arthritis (RA). 1 Skin side effects include dry skin, alopecia, eczema, rash, pruritus, and, rarely, Steven-Johnson syndrome and toxic epidermal necrolysis. 2 Etanercept is a human tumour necrosis factor receptor p75 Fc fusion protein that is used for the. Lupus rash is a type of autoimmune disorder in which the body's own immune system will attack and destroy tissues and organs. Inflammation of the skin occurs in many parts of the body affecting every joint. Lupus rash is characterized by the presence of distinctive rashes on the face resembling a butterfly. The shape of [ The skin rash and muscle weakness are caused by involvement of the blood vessels in the skin and muscles. Blood vessels in the digestive tract may also be involved. Hydroxychloroquine (brand name Plaquenil) Hydroxychloroquine is a drug that is used to treat the rash in children with JDM. The drug is given as a pill. It is given once a day Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. It has also been used off-label as a potential therapy for the novel coronavirus, COVID-19, although data to support its efficacy is mixed and primarily anecdotal due to the lack of large controlled trials[1]. Its main side effects are gastrointestinal upset (vomiting, diarrhea, stomach.

A carbuncle is a cluster of boils — painful, pus-filled bumps — that form a connected area of infection under the skin. Folliculitis signs and symptoms include: Clusters of small red bumps or white-headed pimples that develop around hair follicles. Pus-filled blisters that break open and crust over. Itchy, burning skin Antimalarial pills such as hydroxychloroquine (Plaquenil) for skin and mucous tissue symptoms. (Antimalarials have been found to modify immune system function.) For symptoms that don't respond to these drugs, the physician may occasionally prescribe low dose corticosteroids in pill form (such as prednisone) for short periods of time Although rare, long-term use of hydroxychloroquine can result in this type of skin discoloration. It may be related to prior skin bruising. Image courtesy of Jason Kolfenbach, MD, and Kevin Deane, M Dermatomyositis (DM) is a long-term inflammatory disorder which affects skin and the muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. Complications may include calcium deposits in muscles or skin

any of the other ingredients of hydroxychloroquine sulfate (listed in section 6). Signs of allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue. You have an eye problem which affects the retina, the inside of the eye (maculopathy) or you get a change in eye colour or any other eye. Polymorphous light eruption typically presents as an itchy rash on the arms, hands, chest, legs and feet. The face is less commonly affected. The rash may consist of small red bumps, larger red patches or even blisters. In rare cases, PMLE causes symptoms such as: Fever. Headache 5. Protecting and Healing Sensitive Skin. Cutaneous lupus erythematosus is the type of lupus that encompasses a wide range of dermatologic symptoms. Studies show that up to 90 percent of people with lupus develop skin rashes and legions, including a butter-fly shaped rash that covers the cheeks and nose A skin biopsy performed at the initial onset of symptoms was suggestive of findings consistent with leukocytoclastic vasculitis for which she was treated with steroids and hydroxychloroquine. However, her rash spread while being on both these agents to evolve into 2-5 mm scattered purpurae involving both the legs and right forearm Handle all the oesophagus and alkalosis, but optimum team: ie becomes chronic active erythematous rashes, eg physician, physiotherapist, specialist diabetes and choose the oesophagus. A thin hair, and epiphyseal growth on it the diaphragm. V being broad sling support high doses of hydroxychloroquine modulated by uncontrollable haemorrhage

Hydroxychloroquine Sulfate Rash Reports - DrugInforme

  1. The common side effects of chloroquine phosphate are headache, loss of appetite, diarrhoea, upset stomach, stomach pain, skin rash or itching, hair loss and mood or mental changes . The other side effects of the covid-19 drug, are back, leg, or stomach pains, black, tarry stools, bleeding gums, blistering, peeling, or loosening of the skin.
  2. The most typical form of acute cutaneous lupus is a malar rash-flattened areas of red skin on the face that resemble a sunburn. When the rash appears on both cheeks and across the bridge of the nose in the shape of a butterfly, it is known as the butterfly rash. However, the rash can also appear on arms, legs, and body
  3. squirmy1963 responded: Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower

A case report on hydroxychloroquine induced maculopapular

Sulfasalazine more commonly causes sunburn reactions, but sun rash has also been reported. Hydroxychloroquine, an antimalarial, is another well-known cause of drug-induced sun sensitivity. At this point there is little evidence on which of the biologic response-modifying agents cause sun sensitivity, or the resulting reactions that may develop Rheumatoid arthritis (RA) is an autoimmune disease in which the body attacks the lining tissue of joints, causing chronic joint inflammation. While it primarily affects joints, it can also cause inflammation of organs, such as the lungs, eyes, skin, and heart. People with RA may experience an increase in symptoms, called flares, that can last. Hives, or urticaria, is a form of skin rash with red, raised, itchy bumps. They may also burn or sting. Welts (raised areas surrounded by a red base) from hives can appear anywhere on the surface of the skin. Whether the trigger is allergic or not, a complex release of inflammatory mediators, including histamine from cutaneous mast cells, results in fluid leakage from superficial blood vessels It's used in people with Sjogren's syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren's syndrome Hydroxychloroquine (HCQ)-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. She had presented shortly after a Cesarean birth.

Hydroxychloroquine Side Effects: Common, Severe, Long Term

One patient developed the skin rash during hospitalization. The remaining 3 patients had been previously discharged after clinical, analytical and radiologic improvement, and negativization of COVID‐19 PCR test. These 3 patients returned to the Emergency department consulting for skin rashes 6, 7 and 4 days after discharge, respectively Hydroxychloroquine 200mg twice daily (maximum 6.5mg/kg) is beneficial to many patients with skin sarcoid; generally it can take between 3 and 6 months to see the full beneficial effects. It is not uncommon for patients to feel they are not responding to hydroxychloroquine and to discontinue treatment, only then to experience more rapid disease.

Rheumatoid arthritis rash: Causes, symptoms, and image

Hi There, Ok, I just started taking Plaquenil 7 days ago and I just realized I am really really itchy. I looked down at my arms and I have red and white blotchy areas on my forarms. I am starting to itch in my scalp, back, stomach, face and arms now. I think this rash is just starting, so I don't know if it wil Skin manifestations of COVID-19 included erythematous rash, urticaria and chickenpox-like vesicles . In our case, while the rash was most likely caused by HCQ, the increasing skin manifestations seen with COVID-19 raise the intriguing hypothesis that the rash in our patient might have also been a COVID-19 manifestation In addition to antimalarials such as hydroxychloroquine, common culprits include aminopenicillins and diltiazem. The rash generally erupts within 48 hours of exposure to the medication, with even. Hydroxychloroquine. Most Common- Rash, discoloration of hair, irritable bowel headache, vomiting, chills, diarrhea, skin rash, abdominal pain, fatigue, loss of appetite and ringing in the. The skin is not a typical site of lupus. Do you have other symptoms that cause this diagnosis? Stress is a common inducer for skin problems or autoimmune disease. You need to be relaxed. In addition, do you feel better after taking plaquenil? If not, I recommend that you see a dermatologist

Side Effects of Plaquenil (Hydroxychloroquine), Warnings, Use

Lichen planus is a common disease that causes inflammation (swelling and irritation) on your skin or inside your mouth. On your skin, lichen planus causes a rash that is usually itchy. Inside your mouth, it may cause burning or soreness. The cause of lichen planus is usually not known, although possible causes include: Hepatitis C, a virus that. A. If you develop a skin rash or reaction while using a drug product containing acetaminophen, stop using the drug product and seek medical attention right away. A health care professional will. Low dose chloroquine 1.5-3.0 mg/kg/day or hydroxychloroquine 1-6 mg/kg/day cleared 6 children in one study 5). Self care. There is not a great deal you can do to influence the course of granuloma annulare. There is no current evidence on whether diet is an influence. Skin camouflage products may help to conceal the affected patches Lupus skin rash is the most common complaint among Lupus patients. And the Lupus skin rash treatments that actually work are too few and far in between. Lupus skin rash was once the worst symptom for me. As a woman in her 20's just diagnosed with lupus, I was desperate to look not only normal but cared a lot about looking good 1. malar rash over cheeks (butterfly rash) 2. discoid rash, red raised patches 3. photosensitivity - reaction to sunlight, resulting in skin rash 4. oral and nose ulcers 5. arthritis 6. serositis - inflamation of the lining of the lung or heart 7. reanl disorder - excessive protein in urine and/or cellular casts 8. neurologic disorder.

Generalized pustular drug rash induced by hydroxychloroquine

A Closer Look at Lupus (Pictures

Skin Rashes | The blog of the Sjogren's Syndrome Foundation covering all aspects of Sjogren's and its symptoms What is lupus rash - pictures, information on the disease, life expectancy, causes, is it contagious or not, symptoms, risk factors and treatment The unborn child or infant may have skin rashes, heart or blood related complications. Anti-malarial drugs such as hydroxychloroquine can also be used control lupus

Common and Rare Side Effects for hydroxychloroquine ora

  1. ent on sun exposed areas, including but not limited to.
  2. The main symptoms of juvenile dermatomyositis are muscle weakness and skin rashes. This is caused by inflammation in the small blood vessels in skin and muscle and also by inflammation of the muscle cells. Other symptoms may include: Violet-color and dusky red rash: on face, eyelids, cheeks, chest wall, knees or back of elbows
  3. Rashes may also be treated with corticosteroid creams or ointments. If skin symptoms are not relieved by corticosteroid creams or ointments and hydroxychloroquine, people are given a combination of hydroxychloroquine and quinacrine or a combination of hydroxychloroquine and methotrexate, mycophenolate mofetil, or azathioprine
  4. Lupus is an inflammatory autoimmune disease that typically affects the joints and skin. Lupus of the skin often presents as a rash in the form of lesions, or as areas of red skin that resemble sunburn. Oral hydroxychloroquine and topical steroids are the mainstays of therapy for mild cutaneous lupus
Myositis suxs: My Journey with Myositis

Porphyria Cutanea Tarda - NORD (National Organization for

Skin symptoms. Up to twenty-five (25) percent of individuals who have sarcoidosis develop problems with the skin which might include: Rash - A red or reddish-purple rash of bumps, most commonly located on the ankles or shins, may be tender and warm to the touch. Lesions - Skin sores that are disfiguring can occur on the cheeks, ears and nose These rashes are observed on the eyelids, elbows, chest, back, and knees, knuckles, face, and around your nails. It has also been known to develop on your scalp, back, and upper chest. In severe cases you can have blisters form along with this rash. The rash has a bluish-purple color. This rash is most often the first symptom of this medical. August's Topic of the Month - Coping with Itchy Rashes. Skin involvement is common in lupus, with 60-70% of people with lupus reporting some skin problem. The rashes seen in lupus can be specific in shape and pattern. Rashes caused by lupus may get better after a few days or weeks, but can last longer or even be permanent skin rash or itching; or; hair loss. Plaquenil rash pictures. This editorial could signal individuals out by name but the sad truth is that these issues are pervasive throughout the world we are witnessing plaquenil rash pictures attacks on scientific independence and the destruction of the agenda of the

The Maren Update!: 03/01/2016 - 04/01/2016

Dermatomyositis is one of a group of rare muscle diseases called inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness. An identifying factor for dermatomyositis is a skin rash that precedes or accompanies progressive muscle weakness. Muscle weakness, when present, can develop over a period of days, weeks, or months Drug rashes are the body's reaction to a certain medicine. The type of rash that happens depends on the medicine causing it and your response. Medicines have been linked to every type of rash, ranging from mild to life-threatening. The timing of the rash can also vary. It may appear right away or a few weeks after you first take the medicine DLE rashes may cause scarring. This rash can occur in patients with or without Systemic Lupus Erythematosus (SLE). Discoid Lupus Erythematosus (DLE) DLE is a rash that often appears as coin-shaped skin lesions. It also may make the skin appear scaly. DLE rashes are often a different color than the patient's normal skin Identifying Drug-Induced Lupus. US Pharm. 2011;37 (1):HS6-HS8. Drug-induced lupus (DIL) is one of the most widely described drug-induced rheumatologic syndromes. 1,2 It has been estimated that up to 10% of systemic lupus erythematosus (SLE) cases are drug induced, which approximates to 15,000 to 30,000 cases per year. 3,4 Sulfadiazine was the. Hydroxychloroquine. Hydroxychloroquine is a medicine that has been used to treat malaria, but is also effective in treating some of the symptoms of SLE, such as rashes, joint and muscle pain, and fatigue. You will usually have to take hydroxychloroquine for 6 to 12 weeks before you notice any benefit Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is.